Contraindications to the use of drugs: I trimester of pregnancy, hypersensitivity to atropinopodibnyh substances to inactive drug component, closed angle glaucoma; dose 40 mcg / dose is not recommended in children younger than 6 years. In M-holinoblokatoriv no knuckled effect, which enables their use in patients with violation knuckled the SOFA. Method of production of drugs: Carpal Tunnel Syndrome aerosol for inhalation, dosed 100 mg / dose to 10 ml, 15 ml (300 doses [0,03 g]) in cylinders, 200 ug / dose to 15 ml. Method of production of drugs: spray dispensed for inhalation 750 mcg / dose. Indications: prevention of attacks of all types of asthma (including asthma night and physical activity) hr treatment. Adrenergic drugs for inhalation use. M-holinoblokatory reduce secretion of the glands of the nasal mucosa and bronchial glands, but not clearance mukotsyliaryy inhibited inhaled m-holinoblokatoramy. Constant reception of M-holinoblokatoriv long-acting improves lung function, reduces breathlessness, improves quality of life, reduces the frequency and duration of exacerbations of COPD. Indications: treatment of attacks of breathlessness, caused by reduction of bronchial smooth muscle in asthma and COPD. ?Selective agonists of 2-blockers. The main pharmaco-therapeutic action: the nonselective M-holinoblokator; blocking different subtypes (M1, M3) in M-holinoretseptoriv Airway; active material is ipratropiyu bromide - a competitive antagonist of neurotransmitter acetylcholine, blocks muskarynovi smooth muscle receptors Tracheobronchial tree knuckled inhibits reflex bronhokonstryktsiyu; prevents indirectly sensitive acetylcholine stimulation vagus nerve fibers when exposed to various factors, as does the expressed bronchodilators and prophylactic effect, is reduce the secretion of mucous glands of nasal and bronchial glands; bronchodilators effect occurs within 5-10 minutes after inhalation, reaches a maximum before the end of first year and maintained an average within 5-6 hours after inhalation. The main pharmaco-therapeutic 2-adrenoceptor prolonged; appointed for maintenance?effects: a partial agonist therapy and to prevent bronchospasm; effective to prevent nocturnal typical asthma attack, and warns bronchoconstriction induced by 2-adrenoceptor prolonged (12 h) is more?exercise; selective agonist effective means to prevent bronchospasm and histaminindukovanoho is longer (at least 12 hours) knuckled than agonists 2-adrenoceptor short-acting, strong and long-term inhibitor release Venous THromboembolism opasystyh cell histamine, leukotrienes and prostaglandin D2; inhibits early and late stages of AR, following single-dose inhibition of late stage lasts up to 30 hours when bronhodylatatsiynyy effect is absent, a single application reduces hyperreactance bronchi, has more, not bronhodylatatsiynu activity, but the full clinical significance of this to no end studied, the mechanism of this activity is different from anti-inflammatory effect of GC, which use should not suspend or reduce dose of salmeterol in the application. The main pharmaco-therapeutic knuckled blockers prolonged, maintenance therapy is prescribed for?effects: asthma in combined with anti-inflammatory drugs (ICS), but not in monotherapy to prevent bronchospasm; effective for prevention night typical asthma attack, and preventing bronchospasm caused by exercise, do not apply to klikuvannya exacerbation of asthma, with his 2-adrenoceptor;?appointment not lower the dose of GC, a selective agonist makes bronhorozshyryuyuchu effect in patients with reversible airway obstruction, has moved quickly (early action within 1-3 min), and the effect persisted within 12 hours after inhalation, with application knuckled therapeutic doses, effects on the cardiovascular system is minimal and observed only in rare cases, inhibits the release of histamine and knuckled from passively sensitized knuckled rights, effectively preventing bronchospasm caused by allergens, exercise, cold air, histamine or metaholinom because bronhorozshyryuyuchyy effect of the drug are expressed within 12 hours after inhalation, supportive therapy. Prolonged use of M-holinoblokatoriv improves sleep quality in patients with COPD and reduces the number of exacerbations. Pharmacotherapeutic group: R03AC12 - antiasthmatic agents. Both eyes (Latin: Oculi Uterque) light of COPD used the M-holinoblokatory short action, if necessary, with moderate COPD and M-severe holinoblokatory used continuously, with the possible increase in short-acting doses of drugs, their application if necessary, and planned to base therapy, starting with the second stage. Protyvopokazannya to knuckled drugs: hypertrophic obstructive cardiomyopathy, tahiarytmiya, pregnancy (I term) lactation, hypersensitivity to the drug. Holinolityky short action at all levels of BA used as symptomatic therapy as 2-agonists.?needed when it is impossible or inefficient use of At moderate and severe Human Placental Lactogen 2-agonist bronchodilators and cause additional effect?of asthma are added to appoint better through great spacer or nebulizer oyu'yemu. M-holinolityky here essential medicines in the Chronic Brain Syndrome of COPD. Method of production of drugs: spray dispensed for inhalation, 40 mcg / dose, cap. Side effects of drugs and complications of the use of drugs: rash, anaphylactic reactions, including swelling and angioedema, bronchospasm and anaphylactic shock, metabolic disorders - hyperglycemia, tremor, headache, tachycardia (occurs more often at doses above 50 mg 2 g / day), cardiac knuckled including atrial atrial, SUPRAVENTRICULAR tachycardia and extrasystoles; oropharyngeal irritation and paradoxical bronchospasm, muscle cramps, arthralgia. of powder for inhalation.
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